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Yes, defile is in the scrabble dictionary

...and is worth 11 points by itself.

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defile

noun

1. A march in a line.

2. A narrow gorge or pass that restricts lateral movement, as of troops.

3. A narrow passage or gorge.

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verb

1. to make unclean or impure as.

2. To corrupt the purity or perfection of .

3. To violate the chastity of .

4. To make physically unclean especially with something unpleasant or contaminating .

5. To violate the sanctity of .

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verb-intransitive

1. To march in single file or in files or columns.

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verb-transitive

1. To debase the pureness or excellence of; corrupt: a country landscape that was defiled by urban sprawl.

2. To make filthy or dirty; pollute: defile a river with sewage.

3. To make unclean or unfit for ceremonial use; desecrate: defile a temple.

4. To profane or sully (a reputation, for example).

5. To violate the chastity of.

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Here are some other words you could make with the letters defile, you can also
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Top Words by points

Points

Word Game

defile

10

Scrabble

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2 Letters

Scrabble® Points

id

3

fe

5

el

2

ef

5

ed

3

if

5

li

2

de

3

3 Letters

Scrabble® Points

led

4

lee

3

dee

4

fil

6

fie

6

fid

7

lei

3

lid

4

lie

3

fee

6

fed

7

die

4

dif

7

elf

6

eld

4

eel

3

del

4

def

7

4 Letters

Scrabble® Points

fled

8

defi

8

deil

5

idle

5

dele

5

delf

8

eide

5

lede

5

flee

7

file

7

feel

7

feed

8

deli

5

diel

5

lied

5

lief

7

life

7

5 Letters

Scrabble® Points

field

9

flied

9

filed

9

felid

9

elide

6

edile

6

6 Letters

Scrabble® Points

defile

10

Found 50 words in 0.19813 seconds