despise

1. To look down on with contempt or aversion .

2. To regard as negligible, worthless, or distasteful.

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1. To dislike intensely; loathe: despised the frigid weather in January.

2. To regard with contempt or scorn: despised all cowards and flatterers.

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Here are some other words you could make with the letters despise, you can also
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Top Words by points	Points	Word Game
despise	10	Scrabble

2 Letters	Scrabble® Points
de	3
id	3
es	2
ed	3
is	2
pe	4
pi	4
si	2

3 Letters	Scrabble® Points
psi	5
pis	5
pie	5
pes	5
pee	5
ped	6
see	3
ids	4
sei	3
sip	5
sis	3
dee	4
ess	3
dis	4
eds	4
dip	6
die	4
dep	6

4 Letters	Scrabble® Points
seep	6
pied	7
pies	6
psis	6
seed	5
deep	7
sees	4
seis	4
seps	6
side	5
sipe	6
sips	6
sped	7
peed	7
peds	7
eide	5
eses	4
esse	4
ides	5
diss	5
dips	7
dies	5
deps	7
pees	6
dees	5
desi	5

5 Letters	Scrabble® Points
seeps	7
spies	7
spied	8
speed	8
sipes	7
siped	8
sides	6
seise	5
seeds	6
pedes	8
peise	7
desis	6
deeps	8

6 Letters	Scrabble® Points
peises	8
peised	9
espied	9
espies	8
dieses	7
seised	7
speeds	9
speise	8

7 Letters	Scrabble® Points
despise	10