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Yes, efficacy is in the scrabble dictionary

...and is worth 22 points by itself.

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efficacy

noun

1. Power or capacity to produce a desired effect; effectiveness.

2. The power to produce an .

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Top Words by points

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efficacy

21

Scrabble

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2 Letters

Scrabble® Points

ai

2

ay

5

ye

5

ya

5

if

5

ef

5

ae

2

fa

5

fe

5

3 Letters

Scrabble® Points

fay

9

yea

6

iff

9

icy

8

ice

5

fie

6

fey

9

eff

9

ace

5

aff

9

aye

6

caf

8

cay

8

4 Letters

Scrabble® Points

yaff

13

iffy

13

cafe

9

caff

12

fyce

12

fife

10

fief

10

fice

9

face

9

ceca

8

8 Letters

Scrabble® Points

efficacy

21

Found 33 words in 0.32895 seconds