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Yes, isseis is in the scrabble dictionary

...and is worth 6 points by itself.

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isseis

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Here are some other words you could make with the letters isseis, you can also
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Top Words by points

Points

Word Game

isseis

6

Scrabble

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2 Letters

Scrabble® Points

es

2

is

2

si

2

3 Letters

Scrabble® Points

ess

3

sei

3

sis

3

4 Letters

Scrabble® Points

seis

4

5 Letters

Scrabble® Points

issei

5

sises

5

6 Letters

Scrabble® Points

isseis

6

Found 10 words in 0.18416 seconds