loosen

1. To release from restraint.

2. To make.

3. To relieve (the bowels) of constipation.

4. To cause or permit to become less strict.

5. To become or looser.

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1. To become loose or looser.

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1. To free (the bowels) from constipation.

2. To free from restraint, pressure, or strictness.

3. To untie or make looser.

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Here are some other words you could make with the letters loosen, you can also
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Top Words by points	Points	Word Game
loosen	6	Scrabble

2 Letters	Scrabble® Points
en	2
ne	2
no	2
oe	2
on	2
os	2
lo	2
el	2
so	2
es	2

3 Letters	Scrabble® Points
ons	3
ose	3
ono	3
one	3
ole	3
oes	3
sol	3
sel	3
son	3
nos	3
noo	3
sen	3
els	3
ens	3
eon	3
loo	3

4 Letters	Scrabble® Points
sone	4
onos	4
ones	4
oles	4
oleo	4
enol	4
eons	4
leno	4
lens	4
lone	4
loon	4
loos	4
lose	4
sloe	4
sole	4
nose	4
nolo	4
noes	4
noel	4
soon	4
solo	4

5 Letters	Scrabble® Points
snool	5
solon	5
oleos	5
noose	5
nolos	5
noels	5
loose	5
loons	5
lenos	5
enols	5

6 Letters	Scrabble® Points
loosen	6