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Yes, lyophile is in the scrabble dictionary

...and is worth 17 points by itself.

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lyophile

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Here are some other words you could make with the letters lyophile, you can also
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Top Words by points

Points

Word Game

lyophile

16

Scrabble

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2 Letters

Scrabble® Points

el

2

pe

4

pi

4

po

4

oy

5

op

4

oi

2

oh

5

oe

2

lo

2

li

2

ye

5

yo

5

eh

5

he

5

hi

5

ho

5

3 Letters

Scrabble® Points

phi

8

hip

8

hie

6

lei

3

ley

6

lie

3

lip

5

lop

5

lye

6

ply

8

pie

5

pho

8

hyp

11

peh

8

hey

9

hep

8

oil

3

ole

3

ope

5

ell

3

ill

3

poi

5

pol

5

pye

8

poh

8

hoy

9

yip

8

yep

8

hoe

6

hop

8

yeh

9

4 Letters

Scrabble® Points

pheo

9

yipe

9

yill

7

yelp

9

yell

7

poly

9

poll

6

pole

6

ploy

9

plie

6

pily

9

pill

6

pile

6

oily

7

elhi

7

heil

7

hell

7

helo

7

help

9

hill

7

hole

7

holp

9

holy

10

hope

9

hype

12

hypo

12

lope

6

lipo

6

lipe

6

lily

7

illy

7

5 Letters

Scrabble® Points

holly

11

ollie

5

hoyle

11

hilly

11

ploye

10

phyle

13

holey

11

hiply

13

helio

8

hello

8

hillo

8

6 Letters

Scrabble® Points

phyllo

14

holily

12

8 Letters

Scrabble® Points

lyophile

16

Found 93 words in 0.30493 seconds