mainframe

1. A large powerful computer, often serving many connected terminals and usually used by large complex organizations.

2. A computer with its cabinet and internal circuits.

3. A large fast computer that can handle multiple tasks concurrently.

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Here are some other words you could make with the letters mainframe, you can also
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Top Words by points	Points	Word Game
mainframe	16	Scrabble

2 Letters	Scrabble® Points
aa	2
ae	2
ai	2
am	4
an	2
ar	2
ef	5
em	4
en	2
er	2
fa	5
fe	5
if	5
in	2
ma	4
me	4
mi	4
mm	6
na	2
ne	2
re	2

3 Letters	Scrabble® Points
aim	5
ain	3
air	3
ama	5
ami	5
ana	3
ane	3
ani	3
are	3
arf	6
arm	5
ear	3
era	3
ern	3
fan	6
far	6
fem	8
fen	6
fer	6
fie	6
fin	6
fir	6
ire	3
mae	5
mam	7
man	5
mar	5
mem	7
men	5
mim	7
mir	5
nae	3
nam	5
nim	5
rai	3
ram	5
ran	3
ref	6
rei	3
rem	5
ria	3
rif	6
rim	5
rin	3
fam	8

4 Letters	Scrabble® Points
afar	7
airn	4
amen	6
amia	6
amie	6
amin	6
amir	6
area	4
aria	4
earn	4
emir	6
fain	7
fair	7
fame	9
fane	7
fare	7
farm	9
fear	7
fern	7
fiar	7
fine	7
fire	7
firm	9
firn	7
frae	7
imam	8
maar	6
maim	8
main	6
mair	6
mama	8
mana	6
mane	6
mara	6
mare	6
mean	6
mien	6
mime	8
mina	6
mine	6
mire	6
naif	7
name	6
near	4
neif	7
nema	6
raia	4
rain	4
rami	6
rani	4
ream	6
reif	7
rein	4
rife	7
rime	6
nare	4
arie	4

5 Letters	Scrabble® Points
afire	8
aimer	7
amain	7
amine	7
amnia	7
anear	5
anima	7
anime	7
arame	7
arena	5
faena	8
feria	8
fermi	10
finer	8
frame	10
frena	8
inarm	7
infer	8
infra	8
mafia	10
mamie	9
mania	7
maria	7
mimer	9
minae	7
miner	7
naira	5
namer	7
ramen	7
ramie	7
ramin	7
reman	7

6 Letters	Scrabble® Points
airman	8
airmen	8
ammine	10
anemia	8
fainer	9
famine	11
farina	9
firman	11
fraena	9
immane	10
infare	9
maimer	10
marina	8
marine	8
merman	10
remain	8

7 Letters	Scrabble® Points
fireman	12

9 Letters	Scrabble® Points
mainframe	16