mainline

1. Being in a principal or well-established position: the mainline churches.

2. Being part of an established group.

3. Being in the .

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1. To take by or as if by injecting into a principal vein.

2. To mainline a narcotic drug.

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1. To inject a drug intravenously.

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1. To inject (a drug, such as heroin) directly into a major vein.

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Here are some other words you could make with the letters mainline, you can also
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Top Words by points	Points	Word Game
mainline	10	Scrabble

2 Letters	Scrabble® Points
ae	2
ai	2
al	2
am	4
an	2
el	2
em	4
en	2
in	2
la	2
li	2
ma	4
me	4
mi	4
na	2
ne	2

3 Letters	Scrabble® Points
ail	3
aim	5
ain	3
ale	3
ami	5
ane	3
ani	3
elm	5
inn	3
lam	5
lea	3
lei	3
lie	3
lin	3
mae	5
man	5
mel	5
men	5
mil	5
nae	3
nam	5
nan	3
nil	3
nim	5

4 Letters	Scrabble® Points
alme	6
amen	6
amie	6
amin	6
anil	4
elan	4
ilea	4
ilia	4
inia	4
lain	4
lame	6
lane	4
lean	4
lien	4
lima	6
lime	6
limn	6
line	4
linn	4
mail	6
main	6
male	6
mane	6
meal	6
mean	6
mien	6
mile	6
mina	6
mine	6
mini	6
nail	4
name	6
nema	6
nine	4

5 Letters	Scrabble® Points
alien	5
aline	5
amine	7
anile	5
anime	7
animi	7
elain	5
email	7
imine	7
inane	5
leman	7
liane	5
liman	7
limen	7
linen	5
linin	5
maile	7
milia	7
minae	7
innie	5

6 Letters	Scrabble® Points
anilin	6
limina	8
maline	8
menial	8

7 Letters	Scrabble® Points
aniline	7
laminin	9
lineman	9
melanin	9

8 Letters	Scrabble® Points
mainline	10