nisus

1. An effort or endeavor to realize an aim.

2. A mental or physical effort to attain an end a perfective urge or endeavor.

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Here are some other words you could make with the letters nisus, you can also
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Top Words by points	Points	Word Game
sinus	5	Scrabble

2 Letters	Scrabble® Points
is	2
nu	2
us	2
si	2
un	2
in	2

3 Letters	Scrabble® Points
sun	3
uns	3
uni	3
sus	3
sis	3
sin	3
nus	3
ins	3

4 Letters	Scrabble® Points
sins	4
suns	4
unis	4

5 Letters	Scrabble® Points
sinus	5
nisus	5