Scrabble Dictionary

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Yes, antagonism is playable

...and is worth 17 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Antagonism" Definition

noun

Biochemistry Interference in the physiological action of a chemical substance by another having a similar structure.
Hostility that results in active resistance, opposition, or contentiousness. See Synonyms at enmity.
The condition of being an opposing principle, force, or factor: the inherent antagonism of capitalism and socialism.
Opposition in physiological action.
Interaction of two or more substances such that the action of any one of them on living cells or tissues is lessened.

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