Scrabble Dictionary

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Yes, antagonize is playable

...and is worth 23 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Antagonize" Definition

verb-transitive

To counteract.
To incur the dislike of; provoke hostility or enmity in: antagonized her officemates with her rude behavior.

verb

To act in opposition to .
To incur or provoke the hostility of .

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