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Yes, challenge is playable

...and is worth 19 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Challenge" Definition

noun

A call to engage in a contest, fight, or competition: a challenge to a duel.
A claim that a vote is invalid or that a voter is unqualified.
A demand for explanation or justification; a calling into question: a challenge to a theory.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
Law A formal objection to the inclusion of a prospective juror in a jury.

verb-transitive

Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.
Law To take formal objection to (a prospective juror).
To call to engage in a contest, fight, or competition: challenged me to a game of chess.
To have due claim to; call for: events that challenge our attention.
To invite with defiance; dare: challenged him to contradict her. See Synonyms at defy.

verb-intransitive

To begin barking upon picking up the scent. Used of hunting dogs.
To make or give voice to a challenge.

verb

To demand as due or deserved .
To order to halt and prove identity .
To dispute especially as being unjust, invalid, or outmoded .
To question formally the legality or legal qualifications of .
To confront or defy boldly .

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