Scrabble Dictionary

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Yes, chaperone is playable

...and is worth 18 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Chaperone" Definition

noun

A protein that assists the non-covalent folding/unfolding and the assembly/disassembly of other macromolecular structures, but does not occur in these structures when the latter are performing their normal biological functions.
Source: Wiktionary
An older person who accompanies other younger people to ensure the propriety of their behaviour, often an older woman accompanying a young woman.
Source: Wiktionary
Any of a class of proteins that facilitate the proper folding of proteins by binding to and stabilizing unfolded or partially folded proteins .
An older person who accompanies young people at a social gathering to ensure proper behavior.
One delegated to ensure proper behavior.

verb

To act as a chaperone.
Source: Wiktionary
To act as chaperone to or for .
To act as a chaperone.

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