Scrabble Dictionary

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Yes, isochromosome is playable

...and is worth 24 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Isochromosome" Definition

noun

An abnormal chromosome in which one arm has been lost and replaced with an exact copy of the other arm.
Source: Wiktionary
A chromosome produced by transverse splitting of the centromere so that both arms are derived from the dyad on one side of the centromere of the parental chromosome and each arm has identical genes arranged in the same order counting away from the centromere.

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