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Yes, isomerism is playable

...and is worth 15 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Isomerism" Definition

noun

The complex of chemical and physical phenomena characteristic of or attributable to isomers.
The phenomenon of the existence of isomers.
The state or condition of being an isomer.
The relationship of two or more chemical species that are.
The relation of two or more nuclides with the same mass numbers and atomic numbers but different energy states and rates of radioactive decay.

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