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Yes, leprosy is playable

...and is worth 13 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Leprosy" Definition

noun

A chronic infectious disease caused by a mycobacterium () affecting especially the skin and peripheral nerves and characterized by the formation of nodules or macules that enlarge and spread accompanied by loss of sensation with eventual paralysis, wasting of muscle, and production of deformities.
A morally or spiritually harmful influence.

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