Scrabble Dictionary

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Yes, lyase is playable

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"Lyase" Definition

noun

Any of a group of enzymes that catalyze the formation of double bonds by removing chemical groups from a substrate without hydrolysis or catalyze the addition of chemical groups to double bonds.

Source: American Heritage Dictionary

An enzyme (as a decarboxylase) that forms double bonds by removing groups from a substrate other than by hydrolysis or that adds groups to double bonds.

Source: Merriam-Webster