Scrabble Dictionary

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Yes, opposite is playable

...and is worth 14 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Opposite" Definition

noun

An antonym.
An opponent or antagonist.
One that is opposite or contrary to another.
Something that is to some other often specified thing.
The additive inverse of a real number.

adverb

In an opposite position: They sat opposite at the table.
On or to an opposite side.

preposition

Across from or facing: parked the car opposite the bank.
In a complementary dramatic role to: He played opposite her.
Across from and usually facing or on the same level with .
In a role complementary to .

adjective

Altogether different, as in nature, quality, or significance: The effect of the medication was opposite to that intended.
Being the other of two complementary or mutually exclusive things: the opposite sex; an opposite role to the lead in the play.
Botany Growing in pairs on either side of a stem: opposite leaves.
Facing the other way; moving or tending away from each other: opposite directions.
Placed or located directly across from something else or from each other: opposite sides of a building.