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Yes, proliferation is playable

...and is worth 21 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Proliferation" Definition

noun

The act of increasing or rising; augmentation, amplification, enlargement, escalation, aggrandizement.
Source: Wiktionary
The process by which an organism produces others of its kind; breeding, propagation, procreation, reproduction.
Source: Wiktionary
The result of building up; buildup, accretion.
Source: Wiktionary
The spread of biochemical, nuclear and other weapons of mass destruction to countries not originally involved in developing them.
Source: Wiktionary

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