Scrabble Dictionary

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Yes, upstate is playable

...and is worth 11 points.

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"Upstate" Definition

noun

The northerly section of a state in the United States.
The chiefly northerly sections of a state.
The chiefly rural part of a state when the major metropolitan area is in the south.

adverb

To, from, or in the northerly section of a state: drove upstate on vacation; went fishing in upstate New York.