Scrabble Dictionary

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Yes, vicissitude is playable

...and is worth 20 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Vicissitude" Definition

noun

A change or variation.
The quality of being changeable; mutability.
The quality or state of being changeable .
Natural change or mutation visible in nature or in human affairs.
A favorable or unfavorable event or situation that occurs by chance a fluctuation of state or condition .

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