Yes, sis is in the scrabble dictionary

...and is worth 3 points by itself.

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sis

abbreviation

1. Secret Intelligence Service (British).

noun

1. Informal Sister.

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sis

3

Scrabble

2 Letters

Scrabble® Points

is

2

si

2

3 Letters

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sis

3

Found 3 words in 0.12622 seconds