loosen

1. To release from restraint.

2. To make.

3. To relieve (the bowels) of constipation.

4. To cause or permit to become less strict.

5. To become or looser.

1. To become loose or looser.

1. To free (the bowels) from constipation.

2. To free from restraint, pressure, or strictness.

3. To untie or make looser.

Here are some other words you could make with the letters loosen, you can also
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Top Words by points	Points	Word Game
loosen	6	Scrabble

2 Letters	Scrabble® Points
en	2
ne	2
no	2
oe	2
on	2
os	2
lo	2
el	2
so	2
es	2

3 Letters	Scrabble® Points
ons	3
ose	3
ono	3
one	3
ole	3
oes	3
sol	3
sel	3
son	3
nos	3
noo	3
sen	3
els	3
ens	3
eon	3
loo	3

4 Letters	Scrabble® Points
sone	4
onos	4
ones	4
oles	4
oleo	4
enol	4
eons	4
leno	4
lens	4
lone	4
loon	4
loos	4
lose	4
sloe	4
sole	4
nose	4
nolo	4
noes	4
noel	4
soon	4
solo	4

5 Letters	Scrabble® Points
snool	5
solon	5
oleos	5
noose	5
nolos	5
noels	5
loose	5
loons	5
lenos	5
enols	5

6 Letters	Scrabble® Points
loosen	6