tweak

verb

1. (transitive)To pinch and pull with a sudden jerk and twist; to twitch.

   “to tweak the nose.”

2. (informal, transitive)To adjust slightly; to fine-tune.

   “If we tweak the colors towards blue, it will look more natural.”

   “Economics is a messy discipline: too fluid to be a science, too rigorous to be an art. Perhaps it is fitting that economists’ most-used metric, gross domestic product (GDP), is a tangle too.[…]But as a foundation for analysis it is highly subjective: it rests on difficult decisions about what counts as a territory, what counts as output and how to value it. Indeed, economists are still tweaking it.”

   “Yet on January 10th, only weeks before the charter was due to come into force, the prime minister said his government was tweaking the draft.”

3. (transitive)To tease, to annoy; to get under the skin of (someone, typically so as to irritate them, or by extension to enamor, frighten, etc).

   “Oh, he loved to tweak people and say things like "Hiya sweetums" to me because that was not exactly de rigueur in front of a bunch of strong feminists. He had this enormous sense of humor. I never knew what he was going to say.”

   “I know what kinds of intervals and melodies tweak people—I know how to make people's skin crawl, how to make them shiver. I can't say it works on all listeners. There are some people, such as overly trained composers and theorists ...”

   ““Russia needs leadership and he knows how to tweak people.” He grinned, “He made a convert of me,” chuckling. “I wanted to lead him by the hand, now I follow him like a puppy dog.””

   “But I know he likes to tweak people. For a while he was giving Colette, the receptionist, a hard time, until she learned to ignore him. But that ability that lets him see how to tweak people makes him a superb salesman.”

4. (US, intransitive, slang)To abuse methamphetamines, especially crystal meth.
5. (US, intransitive, slang)To exhibit extreme nervousness, evasiveness when confronted by authorities, compulsiveness, erratic motion, excitability, etc, due to or mimicking the symptoms of methamphetamine abuse.
6. (broadly, intransitive, slang)To be extremely confused; to have no clue what is happening.

   “Am I tweaking or does 2020 feel like 6 months ago?”

   “If you didn't think that was a good halftime show you're actually tweaking”

   “Some of yall gonna think im tweaking but FRONTIER>>>>>>HUENEME”

   “Am I tweaking or did twitter just go offline for 2.5 seconds🤔😅”

   “are these the same color or am i just tweaking”

7. (uncommon)From a catapult, to strike a target with a missile.

noun

1. A sharp pinch or jerk; a twist or twitch.

   “a tweak of the nose”

2. A slight adjustment or modification.

   “He is running so many tweaks it is hard to remember how it looked originally.”

3. Trouble; distress; tweag.
4. (obsolete, slang)A prostitute.

   “Thence to Bautree, as I came there, From the bushes near the lane, there Rush'd a tweak in gesture flanting With a leering eye, and wanton: But my flesh I did subdue it Fearing lest my purse should rue it.”

5. (slang)Methamphetamine.
6. (slang)A single inhalation of cocaine.
7. An additional input to a block cipher, used in conjunction with the key to select the permutation computed by the cipher.